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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dd54c7ad5e4c9b23558cb22e8f716496837fc55e120fbb1fd584664b59d9326' 
  AND token = 'ifostqtxPriFuOqzyluOdZHI7GT2sx88+fmoG6zeUuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}