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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '051566b4970c232f0ec79dddd9e1a890642e9e782fbfd30acb70c0c039a015a4' 
  AND token = 'Qgv1zOZZDNFwP+pYrnmfSUUdCITgkoEGo2cmYqlyA+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}