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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ff042bd8b95001342a9d9763142b23789e9933a55efd89941743dd18ba74df8' 
  AND token = 'GrxqSsLAkYFaPv5OTm/ONJkXGIT4Ec5zrs1f/W93ZjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}