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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434273ce547b71c3a0ac4b3209c9491c132109ef299458cf58773ba8801a8828' 
  AND token = 'fLaw76uCmaKY7sptQJgs8Vjxbr4d+WL65vm7k9aVY3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}