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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5e56146ecab2935e66b367373787eee173daf6b1e4990590bf5ffc35f9d91e' 
  AND token = 'LXCHqbiyW0zkTGjkVNaCPV3CJtQmDIo8y33CUM+BYnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}