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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bee40e8d7234c2b793646a137942640895f490242d9496e57b2f1f78acb6f49e' 
  AND token = 'Ff1GJNHsZLxas4wuP1rjJWTOZBWmUZMhxbkIDoW+sP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}