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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6553b65a396ad8dc38192507f4888ba8e80c11613e5e90982a49f92b38fb7433' 
  AND token = 'sqyJJmP+wSKEu08Qof+FIprdXr6yDddo64Xkh1e7W/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}