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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3575fd956f05c296927a3cbd73bb40c7b2722a4022b41aa8636a6c24d3f35812' 
  AND token = 'UdI1luJrL3hpDTPenuDZusXLlWdm1XVTC4wvV7tbXcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}