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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e149a386826fb6492ff98066bf761bae527d93e340cd868792a8684c1654e551' 
  AND token = 'CyqomYMB8kSSoUhR0k1I6tz7+F5xN8iCT2X8Z1pE2IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}