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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b82914a74de052556b1c69f76c1814d4284ad9a1710635e6b9d8e92ac05a90e' 
  AND token = '/LF7NQ5Hpa3XH+E33NFFV5rEdHabkv9lmdXBcXbPqGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}