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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0688de0df7baf347b20b6914893bc8305b795fe5028c528a5a4aba1d47e55ccc' 
  AND token = 'K6D+i2yHzUzvES1gz4oH22b9nRd/+6ZZ9mk50+cdrjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}