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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '049ff2f916e27e4ee8ad36423c5932aff4164b1dff1fe0ea875ebe78738714d4' 
  AND token = 'rpkIhWFyyiDF58+WvWS+fwM9Wgp42Hma7q+m2UyOf9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}