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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0f99dc01e37f4161b2d226fc4dc809f0eb0a9b50fcf78fef73de40ce790600' 
  AND token = 'i3Exmvz4LXPLU48krnLPV/UzyZqg5xrjJb7uYoDb/gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}