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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69ce0dcea2e5750f6016529e738e5891ebffcad596c0a14500ed1cf7e12f03ab' 
  AND token = 'uTMZWfwKM1+BV4hqA745fN9Fjo86OOV/4LDt3oef4Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}