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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bd95afd705be39ce35c18de2006f3710cf5622fad75a4333e43a19a0f4e48a4' 
  AND token = 'oV2wfpnPsHJ8S1LJ06MxX4btwMWBVtOR5qBpnKpCBUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}