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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e77f1f99f5e00b0730f0eba3f2a0bc190056ca811ff0af002ee12f8b8641b3c' 
  AND token = '6nx4NqQO8r5nLdlHT9hlWcj7ufXvv7Rh/WjMKrv1S10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}