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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cf5644a89f6bb7ef1aa5028e4ac6757b24ed633fabeb6ce0e00c450775d70f9' 
  AND token = 'eOriVch9bHYNcmxqosLmH6tN3v6f25kl5bmpvSZlaOk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}