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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309034311a1937c071604ad8de660b8d6e3673acfd2d721fd259c7bb0be5a11b' 
  AND token = 'are9XY2YdAAZ/MDNE/9WF6Q7HGZ2iWO/c49ElsOTsuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}