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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb214c8b01dc835704f0ef610ed73eb648bc25bdd348e08a02537f0b5e6e016' 
  AND token = '5dtGs+XMh252y+zTjvzMdc8w3fLTNfgHx5uzjDSPUeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}