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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7c2c63cb3d61f99f08eb3086408a503cb6144c107a1a6daeac68650eddb694' 
  AND token = 'GVRuTFiQoj0b0KjTISg3r63kFmlN7r46LO85lTZBtMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}