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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f29b355e69452631b3a16e0cdf00f6beebc142adc54131d5bed37ec1373a7b' 
  AND token = '/QmnS/oIBnGtoF58dE0MxrPakuGzwKupT2B1uisFzOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}