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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88a935f81c51eb1fabf3c15a6710174b07b5ab9f8dda5c168f021927729d56f' 
  AND token = 'v+1PcS6sPd9tw8/SWjyocZYHxZql15RIIbuuCJ2nmBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}