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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b54787436613d99e1fe17e623b114f8e9a8d9dc5fd71c2d5db330ecdf132063' 
  AND token = 'oWzqOA2WOVf/dI5UGhDEqGXpVHOGhCtxBh426bn4jaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}