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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f66165b8ed2a00b8329cb4994d0669936c743901dcf5c6a3a3e47497d41cb57' 
  AND token = '9TGYI2G2yGgo1tLXmf45UcCL2bYUz7cGmHxJd2TbJH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}