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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d24d96b2928be5f07dcbe3132d5a487c5aeaee80806b1fc4f189f40cf2a2e50' 
  AND token = 'fzacHeAx6VaUM5Y0kRa01+gJIwdmJ4Gow33a8XgSlBA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}