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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5be10a0a46ad174b4c46679671fd472860f608c38d3c4f23dc628f76bfa018e' 
  AND token = 'oVTt18tqpB9QiA4XMw8e421iLltolp8JfZUPOzmYmd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}