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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f546284223b107f71a934ef584a69a273ac1413316ad6dcc267b9537a1c3e55' 
  AND token = '1ON64q3fJMCeJe4ynwEN1+kFUyqrCL6m1oLvNbl1vn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}