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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c6f2f840da4af045c9ac375c5873199f88773f233169efe33bf7847e54af32' 
  AND token = 'NURYJgc4/j21/rh6NOeeJGyvF5N2uMfygwWECpimX2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}