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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1494cf372b6f3c2690a05befeb59f5d0266fd0000561db2b75d3568f7a3c3e99' 
  AND token = '2bqX6ZjxGz7JKXrUteeL0qijo8LCXlPBAjDaxLXJSv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}