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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4540b83b0c51933055a43a8a69e8a043cdc3b91d0e587f8eb4810994a1b44746' 
  AND token = 'LR65zoyIqQyBd+M02VEDUJ+6LhQw9ApRwMgF7u71O8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}