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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fddc122de160f9bc06b87cc04b4060ed7dda5416bc9c8a33679d6b9b1ebd1187' 
  AND token = 'D1Zm9cE3Ec/cLptL743D9FdaPl8bOHWbBrDrC2CKOew=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}