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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea78c6b1a71db27d781b5cccf71f8d750518d76fc923219e78c0084764f58aa' 
  AND token = 'Os2GWRY8L8DtQmTQjzcWG0e06bJhXozXOSMq4yXDo+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}