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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8f858c4661eeb273c447c87b416e981ca81453bb6a62150298e92afa7729cd5' 
  AND token = '+IgOrH8U2sItkf1t88g8WM5oCVl92HASgbdCT9BMPt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}