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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be8532279442b417fb182e57beae75f2864522e74a56eb643c13d668353b3490' 
  AND token = 'WqdhYj4VAjUNoOwl09TGeeJ50ElWksfTYB6hkyDKxXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}