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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59e09410840de1b2c99e23bc2f45e925e0cc50b4d19a06c2e63269f926cd3cad' 
  AND token = 'sBO2Rytt6fmRZ5TdKBnYfwaqawaKPkJ6h3/n0dM92pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}