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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e54c37902b237ef9a20c24b8a49ee20f32d0360b424f45f4341eebbc5369f855' 
  AND token = 'XtLD2g/ocqlihzjNqUeK/PZ321VYn3fZuCFZNzdl85Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}