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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2708abdef20c39a9eb1e8140317da93a75648ebb7719bc57e2d4d0b420d436c' 
  AND token = '/xM7bDDaKw3CLU3c1VIvf8dfm5wWSulMPdw1vC/kfN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}