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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d8ea4fd47bdef9471d7eb591a903181b3436001ec6519d93044beb6b0a1f20' 
  AND token = 'rKj+QHWTZmXNzLQt5+I/qIRR0Q0YUlIvrM+gPyjq2m0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}