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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7a9774072dd99a885ddcdfec78f71661f1b65c64f0f75a97b5527bdaf521422' 
  AND token = '5bxTtCT35Mu2SOiFO/Uri0ldcDChtdmuq6Lgy4DysKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}