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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd82e9e5348d6719df650be8c84cba20461870394c35cbbc1f972ba97d7b7988' 
  AND token = 'IedApRhFfC+NCZklFJiMQvzz/+lhROfIi4x2ax1UQq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}