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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50869eccd13af4bf40803fe1d5c03372f528453443d2df03300b54f4427dfb9' 
  AND token = 'qYUpyQ/+WuhVTLQPqTJK80dK/e8ssqolxNDm3g5+1Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}