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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c160c7fb6a3e92f049d59044257cc269899344804e5a6e2297abf17c7658e45' 
  AND token = '7ASDYTp/zvI3Fq4wGV5Tvb0gjMnO2ITsWzIrakYW/Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}