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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41ca80dc4f940d4ae840b2d43c6e9bac9f169f82184b4211160efd5c8e28448f' 
  AND token = 'Uz5dfsb+2WZrYl6BVGXpGr+m6Xj8ibiiQO4X2ehdaio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}