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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b56a52095c5d364460d7c98dd710599e9c617cf12683c26c9bfcdde83cd3e09' 
  AND token = 'VZJ3dqxRmBPKJQx/lem5nDc3lw1L+Eu0YcaYbfNL27E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}