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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4addb81efe61930868565dd5c146e559516f9f4772d034f9b120de8c629c50a' 
  AND token = 'G+Z07oXyczNmYCNSc3tfWewzprCJ2lmKirM0MINSrZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}