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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b535215f2e22e6cc131275b7c17cff1a074d63995bd1cb559d04b7a55702f7d3' 
  AND token = 'W4Q9jLQnmCIpK3iZ8njnvEWXuAMk/60V+skUHDIBP3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}