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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e5cc17f84314ed581a1f60042a8cd54fb0a0f424b46e93df9f644497153aa4' 
  AND token = 'zjGxhXrTLtvkLl8DSk1hfUXAXtQry6HzS1wr6YOW0nE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}