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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6138046f6e81dba504368f08541a38a8c356fe3bd3a04c2c0fe7b99314b85295' 
  AND token = 'pUkqJOhHBi9Mq5wivYxMkSCx9qvSc4HJYAIzPaEMvLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}