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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06053e7ff8bbbe1a54c122b9b2f3d2314ac2f8f10f71df330d6821913cc39405' 
  AND token = 'QtDwkOo+EEx8eDxgiwoymdAUZriYzPa2GubSxRLJzak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}