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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e188581b9f966b01af7e023f9c1133efd41cfb0c96312c14a03f430de003107' 
  AND token = 'YCng22Plhs7T684eB4N0idmSuoO4M7CqfNP1a1G9Xoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}